What is Magnetic Bead Nucleic Acid Extraction?

Since the birth of Watson and Crick's DNA double helix model, biology has entered a new era. In biology, DNA must be discussed, and the central dogma must be discussed. The basis of scientific research in all disciplines, with the rapid development of genetic diagnosis, genetically modified food testing, personalized medicine, etc., the current nucleic acid extraction technology can no longer meet the needs of today's biotechnology, and high-throughput, automated nucleic acid extraction methods are urgently needed. . In this context, the magnetic bead method for nucleic acid extraction came into being. 

What is Magnetic Bead Nucleic Acid Extraction?

The magnetic bead method for nucleic acid extraction has the incomparable advantages of traditional DNA extraction methods, mainly reflected in:

① It can realize automatic and large-scale operation. At present, there are 96-well nucleic acid automatic extraction instruments, which can be realized in the extraction time of one sample. The processing of 96 samples complies with the high-throughput operation requirements of biology, enabling rapid and timely response to infectious disease outbreaks, which makes traditional methods unmatched;

②  The operation is simple and time-consuming, and the entire extraction process has only four steps , most of them can be completed within 15-20 minutes;

③  Safe and non-toxic, no toxic reagents such as benzene and chloroform in traditional methods are used, and the damage to experimental operators is minimized, which fully conforms to modern environmental protection concepts;

④  Magnetic beads and nucleic acids The specific binding of the extracted nucleic acid results in high purity and high concentration of the extracted nucleic acid. 

The magnetic bead method nucleic acid extraction kit is a high-tech product combining biological science and nanomaterial science. It is a major breakthrough in my country's nucleic acid extraction and purification technology. Nucleic acid extraction kit-EN (4) - 副本

The principle of nucleic acid extraction by magnetic bead method

According to the same principle as the silica membrane spin column, the superparamagnetic silicon oxide nano-magnetic beads are prepared after the surface of the superparamagnetic nanoparticles is modified and modified by nanotechnology. The magnetic beads can specifically recognize and efficiently bind to nucleic acid molecules on a microscopic interface. Using the superparamagnetic properties of silica-coated nanomagnetic microspheres, under the action of Chaotropic salts (guanidine hydrochloride, guanidine isothiocyanate, etc.) and an external magnetic field, samples from blood, animal tissues, food, pathogenic microorganisms, etc. The isolated DNA and RNA can be used in clinical disease diagnosis, blood transfusion safety, forensic identification, environmental microbial testing, food safety testing, molecular biology research and other fields. 

Magnetic bead method nucleic acid extraction process

Magnetic bead method nucleic acid extraction can generally be divided into four steps: lysis-binding-washing-elution. 未标题-1

The industry driving role of magnetic bead nucleic acid extraction

Genetic testing is bound to become a new symbol of the development of the biological industry. The emergence of high-throughput, automated nucleic acid extraction methods has reduced the labor cost of genetic testing, made large-scale testing a reality, and made it possible for genetic testing to reach ordinary people. 

Manufacturer of Magnetic beads nucleic acid extraction:

Geneture medical specialized in the field of nucleic acid extraction  and PCR detection system, main products involved in:

1.Nucleic Acid Extraction Kit (Magnetic beads method)

2.Nucleic Acid Extractor (32T, 96T)

3.PCR fluorescence quantitative analyzer (16T, 96T)

4.PCR detection reagent

5.SARS-CoV-2 antigen rapid test kit

6.Lab consumables: deep well plate, mag-rod sleeve, pipette tips, VTM, swabs, PCR tubes, PCR plate, centrifuge tubes, cryogenic Vials, saliva collection and so on.

Please don’t hesitate to contact with us to get a quotation.