Geneture Gene Sequencing Kit

GenetureSeq Prep Kit-Pan-solid Tumor 768 Panel

Pan-solid Tumor 768 Panel contained more than 768 genes designed by NCCN, FDA, COSMIC and other databases. It contained tumor genes, HLA-related typing genes, common chemotherapy guidance sites, MSI sites, and a total of 1.3M region.

Based on liquid phase hybridization capture and next generation sequencing technology, a variety of mutation information, including point mutation, insertion/deletion, amplification, copy number variation, microsatellite instability, and tumor mutation burden, can be detected in solid tumor tissue, blood cfDNA and other samples in a single experiment, so as to guide chemotherapy, targeted drugs, and immune drugs for tumor patients.

 

Model96T


Product Features:

1. Comprehensive: covering 768+ genes, including common tumor genes, HLA typing genes, MSI loci, and common chemotherapy drug guidance sites, taking into consideration the core gene CDS region and hot gene SNP sites.

2. Strong compatibility: Illumina platform and MGI platform are applicable.

3. Fast: support 1-4 hours rapid hybridization, and maintain excellent performance.

4. Flexible: support multiple miscellaneous, improve the utilization rate of reagents.

 

Storage Condition:

The reagent was composed of three parts, Part1 and Part3 need to be transported at -15 ℃ to -20 ℃ and valid for 12 months at -20±5 ℃. Part2 needs 2~8℃ constant temperature transportation, valid for 12 months at 2~8℃.


Additional Information

Standard test results

Gene

AF%(gene)

AF%(ddPCR)

AF%(two-fold dilution
/ddPCR)

AF%(two-fold dilution
/768)

EGFR L858R

1.00%

0.98%

0.50%

0.50%

KRAS A146T

1.00%

0.90%

0.50%

0.60%

NRAS Q61K

1.00%

1.13%

0.50%

0.60%

EGFR T790M

2.00%

2..08%

1.00%

0.90%

EGFR ΔE746_A750

2.00%

2.04%

1.00%

0.80%

FLT3 ΔI836

2.00%

1.87%

1.00%

0.70%

KIT D816V

2.00%

2.00%

1.00%

1.10%

KRAS G12D

2.00%

1.93%

1.00%

0.80%

EGFR insASV

3.00%

2.54%

1.50%

1.30%

EGFR G719S

4.00%

4.18%

2.00%

1.80%

KRAS G13D

4.00%

3.60%

2.00%

1.90%

BRAF V600E

7.00%

6.48%

3.50%

2.80%

PIK3CA H1407R

7.00%

7.00%

3.50%

3.30%


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