Introduction to Nucleic Acid Extraction with Magnetic Beads Details

Introduction to Nucleic Acid Extraction with Magnetic Beads

With the rapid development of genetic diagnosis, genetically modified food detection, and personalized medicine, the current nucleic acid extraction technology can no longer meet the needs of today's biotechnology, and a high-throughput, automated nucleic acid extraction method is urgently needed. In this context, the nucleic acid extraction magnetic bead method came into being.

The principle of nucleic acid extraction by magnetic bead method

According to the same principle as the silica membrane spin column, the superparamagnetic silica nanomagnetic beads are prepared after the surface of the superparamagnetic nanoparticles is modified and modified by nanotechnology. Magnetic beads can specifically recognize and effectively bind nucleic acid molecules on microscopic interfaces. Using the superparamagnetic properties of silica-coated nanomagnetic microspheres, under the action of chaotropic salts (guanidine hydrochloride, guanidine isothiocyanate, etc.) and an external magnetic field, samples from blood, animal tissues, food, pathogenic microorganisms, etc. The isolated DNA RNA can be used in clinical disease diagnosis, blood transfusion safety, forensic identification, environmental microbial testing, food safety testing, molecular biology research, and other fields.

Advantages of Magnetic Bead Nucleic Acid Extraction

①It can realize automation and large-scale operation. At present, there are 96-well nucleic acid automatic extractors, which can process 96 samples within the extraction time of one sample, which meets the operational requirements of high-throughput biology and enables infectious diseases to have rapid and timely response capabilities in infectious diseases. Once it breaks out, traditional methods cannot be compared;

②Simple operation and short time. The entire extraction process has only four steps, most of which can be completed within 36-40 minutes;

③ Safe and non-toxic, no toxic reagents such as benzene and chloroform in traditional methods are used, and the damage to the experimental operators is minimized, which fully conforms to the modern environmental protection concept;

④ The specific combination of magnetic beads and nucleic acid makes the extracted nucleic acid with high purity and concentration.

Professional magnetic bead nucleic acid extraction supplier

GENETURE is a group company focused on clinical diagnostics and life sciences. We have two factories. Provide nano-biological magnetic beads as the core, including nucleic acid extraction kits, nucleic acid extractors, magnetic beads, PCR kits, PCR systems, and other products and services. Our company has passed ISO9001 and ISO13485 certifications, and the reagents and instruments have obtained CE and FDA certifications.

Just tell us your requirements, and we will provide solutions and provide you with strong market backing, relying on strong production capacity and strict quality control to serve customers.